50. A critical situational decision needs to be made about whether to continue a clinical trial for a new drug that has shown very small, but statistically significant, benefits in early analyses. What urgency is involved in considering both statistical and clinical significance?

To immediately stop the trial because of small benefits.
To weigh the statistical significance against the clinical relevance and potential harms, recognizing that a statistically significant effect may not be clinically meaningful.
To continue the trial regardless of clinical significance.
To only consider the p-value.

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