- Excessive production of lactic acid.
- Impaired alveolar ventilation and CO2? retention.
- Loss of bicarbonate from the kidneys.
- Overproduction of ketone bodies.
54. A patient with uncompensated respiratory acidosis (e.g., due to severe COPD exacerbation) has low blood pH and high PCO2?. What is the technical primary pathophysiological cause of the acidosis?
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