- A smaller sample size will be needed.
- A larger sample size will be needed to detect a statistically significant difference.
- The standard deviation is irrelevant to sample size.
- The study should be abandoned.
27. A medicinal study is designed to compare the effect of a new drug versus placebo on a continuous outcome. If a large standard deviation is observed in the preliminary data, what critical implication does this have for the required sample size?
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