40. In a critical situational context, a statistician identifies that a dataset contains significant missing values, particularly for a key outcome variable. What is the urgency from a biostatistical perspective?

  • To immediately impute all missing values.
  • To investigate the pattern of missingness and assess its potential impact on bias and the validity of results.
  • To ignore the missing values if they are less than 5%.
  • To discard all records with missing values.
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