A patient with a severe bacterial infection develops systemic inflammatory response syndrome (SIRS) and then progresses to septic shock. The key pathophysiological event in septic shock is:
A.
Massive vasodilation and increased capillary permeability due to inflammatory mediators.
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B.
Direct myocardial tissue damage.
C.
Pulmonary embolism.
D.
Hyperglycemia due to insulin resistance.
📖 Additional Information
Massive vasodilation and increased capillary permeability due to inflammatory mediators.