Practice Questions

Which statement best explains why cartilage is present in the embryonic skeleton before most bones develop?

A. Cartilage is harder than bone
B. Cartilage provides a flexible framework that is later replaced by bone ✓
C. Cartilage contains more calcium salts than bone
D. Cartilage permanently replaces all bones after birth

Correct: Most embryonic bones develop from cartilage through endochondral ossification. A: Bone is harder than cartilage. C: Cartilage contains fewer mineral salts. D: Most cartilage is replaced by bone before adulthood. Concept: Embryonic skeletal development and ossification.

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Jul 27, 2026

Correct: Collagen provides tensile strength and flexibility. Without it, bone becomes brittle. A: Rigidity depends mainly on minerals. C: Minerals are stored in the matrix. D: Osteons are structural units, not formed by collagen alone. Concept: Organic matrix of bone.

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Jul 27, 2026

Which characteristic is common to both cartilage and bone?

A. Presence of Haversian canals
B. Rich blood supply
C. Cells embedded in an extracellular matrix ✓
D. High concentration of elastic fibers

Correct: Both tissues are connective tissues with cells embedded in a matrix. A: Only bone has Haversian canals. B: Cartilage is avascular. D: Elastic fibers are mainly found in elastic cartilage. Concept: Comparison of connective tissues.

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Jul 27, 2026

During an experiment, equal forces are applied to a bone and a cartilage sample. The cartilage bends while the bone remains rigid. The difference is mainly due to the:

A. Presence of collagen only in cartilage
B. Greater mineral content of bone ✓
C. Presence of osteocytes in cartilage
D. Absence of matrix in cartilage

Correct: Bone contains abundant calcium salts that provide rigidity. A: Both tissues contain collagen. C: Osteocytes are bone cells. D: Cartilage has a well-developed matrix. Concept: Mechanical properties of bone and cartilage.

nmdcat.online BIO NMDCAT
Jul 27, 2026

If osteoclast activity greatly exceeds osteoblast activity over a prolonged period, the most likely outcome is:

A. Increased bone density
B. Reduced bone mass and increased fracture risk ✓
C. Excess cartilage formation
D. Increased muscle strength

Correct: Osteoclasts resorb bone; excessive activity weakens bones. A: Bone density decreases. C: Osteoclasts do not form cartilage. D: Muscle strength is unrelated. Concept: Bone remodeling.

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Jul 27, 2026

A patient suffers degeneration of cartilage covering the ends of bones. Which consequence is most likely during movement?

A. Increased production of bone marrow
B. Increased friction between bones ✓
C. Increased calcium storage
D. Increased bone flexibility

Correct: Loss of articular cartilage increases friction, causing pain and restricted movement. A: Bone marrow production is unrelated. C: Calcium storage is unaffected. D: Bone flexibility does not increase. Concept: Function of articular cartilage.

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Jul 27, 2026

During microscopic examination, a tissue contains concentric lamellae surrounding a central canal. The tissue is identified as:

A. Elastic cartilage
B. Hyaline cartilage
C. Compact bone ✓
D. Fibrocartilage

Correct: Compact bone consists of osteons with concentric lamellae around Haversian canals. A, B & D: Cartilage lacks osteons and Haversian canals. Concept: Histology of compact bone.

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Jul 27, 2026

A surgeon removes the periosteum from part of a bone. Which function of the bone is most likely to be affected first?

A. Production of blood cells
B. Increase in bone thickness and repair ✓
C. Storage of calcium salts
D. Protection of internal organs

Correct: The periosteum contains osteoblasts responsible for appositional growth and fracture repair. A: Blood cells are produced in bone marrow. C: Mineral storage continues in existing bone. D: Protection remains unless bone is damaged. Concept: Role of periosteum.

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Jul 27, 2026

Compared with compact bone, cartilage is better suited to absorb compressive forces because its matrix is:

A. Highly mineralized
B. Flexible and rich in chondrin ✓
C. Organized into osteons
D. Richly supplied with blood vessels

Correct: Chondrin gives cartilage resilience and flexibility for shock absorption. A: Mineralization makes bone rigid. C: Osteons are bone structures. D: Cartilage is avascular. Concept: Structure-function relationship of cartilage.

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Jul 27, 2026

During growth, a child’s long bones increase in diameter mainly due to the activity of:

A. Chondrocytes of epiphyseal plate
B. Osteoblasts beneath the periosteum ✓
C. Osteoclasts in the medullary cavity
D. Osteocytes within lacunae

Correct: Osteoblasts beneath the periosteum deposit new bone on the outer surface, increasing bone thickness. A: Chondrocytes increase bone length. C: Osteoclasts resorb bone. D: Osteocytes mainly maintain bone tissue. Concept: Appositional growth of bone.

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Jul 27, 2026
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