100. A patient with asthma is exposed to an allergen and develops an acute exacerbation. What is the technical primary pathophysiological response that leads to bronchoconstriction?
A.
Increased production of surfactant.
B.
IgE-mediated mast cell degranulation and release of bronchoconstrictive mediators (e.g., histamine, leukotrienes).
✓
C.
Activation of macrophages.
D.
Inhibition of smooth muscle contraction.
📖 Additional Information
Increased production of surfactant.
IgE-mediated mast cell degranulation and release of bronchoconstrictive mediators (e.g., histamine, leukotrienes).
