110. In clinical screening, if a disease has a very low prevalence in a population, what critical impact does this have on the Positive Predictive Value (PPV) of a screening test, even if the test has high sensitivity and specificity?
A.
PPV will be very high.
B.
PPV will be very low, leading to many false positives.
✓
C.
PPV will be unchanged.
D.
PPV becomes irrelevant.
📖 Additional Information
PPV will be very high.
PPV will be very low, leading to many false positives.