133. A critical situational public health official is considering implementing a widespread screening program for a rare disease. A biostatistician advises that even a highly sensitive and specific test may yield many false positives in this context. What urgency is involved?
A.
To immediately implement the program.
B.
To urgently explain that for rare diseases, a high positive predictive value (PPV) is difficult to achieve, leading to unnecessary anxiety and follow-up for many healthy individuals.
✓
C.
To ignore the concept of false positives.
D.
To use a less sensitive test.
📖 Additional Information
To immediately implement the program.
To urgently explain that for rare diseases, a high positive predictive value (PPV) is difficult to achieve, leading to unnecessary anxiety and follow-up for many healthy individuals.
