BS Nursing Pharmacology-I
nmdcat.online June 6, 2026

15. A patient on long-term NSAID therapy for arthritis develops gastric pain. Technically, what is the mechanism by which NSAIDs can cause gastrointestinal ulcers?

A. Increasing gastric acid secretion.
B. Inhibiting COX-1, leading to reduced protective prostaglandin synthesis.
C. Stimulating histamine release.
D. Direct irritation of the gastric mucosa.

📖 Additional Information

  • Increasing gastric acid secretion.
  • Inhibiting COX-1, leading to reduced protective prostaglandin synthesis.
  • Stimulating histamine release.
  • Direct irritation of the gastric mucosa.

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