15. A patient on long-term NSAID therapy for arthritis develops gastric pain. Technically, what is the mechanism by which NSAIDs can cause gastrointestinal ulcers?
A.
Increasing gastric acid secretion.
B.
Inhibiting COX-1, leading to reduced protective prostaglandin synthesis.
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C.
Stimulating histamine release.
D.
Direct irritation of the gastric mucosa.
📖 Additional Information
Increasing gastric acid secretion.
Inhibiting COX-1, leading to reduced protective prostaglandin synthesis.