193. A critical situational clinical trial is planned to assess a new drug. The biostatistician notes that the proposed sample size is too small to detect a clinically meaningful difference. What is the urgency for intervention?
A.
To proceed with the small sample size.
B.
To urgently advise that an underpowered study is unethical and a waste of resources, as it has a high chance of missing a true effect (Type II error).
✓
C.
To only consider the cost of the trial.
D.
To assume the drug will work anyway.
📖 Additional Information
To proceed with the small sample size.
To urgently advise that an underpowered study is unethical and a waste of resources, as it has a high chance of missing a true effect (Type II error).
