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23. A patient with a severe allergic reaction (anaphylaxis) presents with widespread urticaria, angioedema, bronchospasm, and hypotension. What is the technical primary mediator responsible for these symptoms?
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25. A patient with chronic heart failure is prescribed a loop diuretic (e.g., Furosemide). From a medicinal perspective, what is the technical pathophysiological mechanism by which this drug reduces fluid overload?
