43. A medicinal study is testing a new drug for a rare disease. What critical challenge does the rarity of the disease pose for sample size calculation?
A.
It makes it easier to recruit participants.
B.
It often necessitates a very large sample size to detect a meaningful effect, which can be challenging to achieve.
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C.
Sample size is irrelevant for rare diseases.
D.
It means the drug will always be effective.
📖 Additional Information
It makes it easier to recruit participants.
It often necessitates a very large sample size to detect a meaningful effect, which can be challenging to achieve.
