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BIO NMDCAT Structure of DNA
nmdcat.online July 3, 2026

69. The spatial asymmetry where the two sugar-phosphate backbones twist around the central axis creates a larger open space called the

A. Minor groove
B. Major groove
✓
C. Central pore
D. Hydrophobic cleft

📝 Explanation

The wider, deeper gap on the outside of the helix is the major groove, which provides easy access for sequence-specific DNA-binding proteins.

📖 Additional Information

  • Minor groove
  • Major groove
  • Central pore
  • Hydrophobic cleft

The wider, deeper gap on the outside of the helix is the major groove, which provides easy access for sequence-specific DNA-binding proteins.

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