BIO NMDCAT Factors that Affect the Rate of Enzyme Reactions

nmdcat.online July 11, 2026

A decrease in pH far below the optimum value causes reduced enzyme activity because

A. The substrate completely disappears

B. Ionic and hydrogen bonds maintaining enzyme structure become disrupted

✓

C. The activation energy becomes negative

D. Product concentration becomes zero

📝 Explanation

Extreme pH alters the ionization of amino acid side chains and disrupts the interactions maintaining the enzyme's tertiary structure.

📖 Additional Information

The substrate completely disappears
Ionic and hydrogen bonds maintaining enzyme structure become disrupted
The activation energy becomes negative
Product concentration becomes zero

Extreme pH alters the ionization of amino acid side chains and disrupts the interactions maintaining the enzyme's tertiary structure.

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