A patient with a severe bacterial infection develops fever. The release of which substances by immune cells primarily causes fever?

A. Antibodies.

B. Endotoxins.

C. Pyrogens (e.g., IL-1, TNF-alpha).

✓

D. Histamine.

📖 Additional Information

Antibodies.
Endotoxins.
Pyrogens (e.g., IL-1, TNF-alpha).
Histamine.

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