A conjugated protein (holoprotein) consists of a protein part (apoprotein) and a non-protein part (prosthetic group). If the prosthetic group is a cofactor and the protein is an enzyme, its removal yields an inactive apoenzyme. The term specifically relates to the loss of the non-protein component.
A conjugated protein (holoprotein) consists of a protein part (apoprotein) and a non-protein part (prosthetic group). If the prosthetic group is a cofactor and the protein is an enzyme, its removal yields an inactive apoenzyme. The term specifically relates to the loss of the non-protein component.