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nmdcat.online June 27, 2026

In the induced fit model of enzyme-substrate interaction, the binding of the substrate to the enzyme causes

A. The enzyme to completely change its primary structure
B. The active site to undergo a conformational change for a tighter fit
✓
C. The substrate to permanently break down before binding
D. The enzyme to be consumed in the reaction

📝 Explanation

Unlike the rigid lock-and-key model, the induced fit model proposes that the active site is flexible. The initial substrate binding induces a conformational change in the enzyme, molding the active site into a precise complementary shape around the substrate.

📖 Additional Information

  • The enzyme to completely change its primary structure
  • The active site to undergo a conformational change for a tighter fit
  • The substrate to permanently break down before binding
  • The enzyme to be consumed in the reaction

Unlike the rigid lock-and-key model, the induced fit model proposes that the active site is flexible. The initial substrate binding induces a conformational change in the enzyme, molding the active site into a precise complementary shape around the substrate.

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