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nmdcat.online June 27, 2026

In the structure of DNA, the strict pairing of adenine with thymine and guanine with cytosine is essential for

A. Forming a strong sugar-phosphate backbone
B. Maintaining a uniform helix diameter and accurate replication
✓
C. Binding RNA polymerase during transcription
D. Providing the energy for polynucleotide synthesis

📝 Explanation

The specific base pairing (A-T with 2 H-bonds, G-C with 3 H-bonds) between a purine and a pyrimidine ensures the two DNA strands are equidistant apart, creating a uniform diameter. This complementarity is also the molecular logic for semi-conservative replication.

📖 Additional Information

  • Forming a strong sugar-phosphate backbone
  • Maintaining a uniform helix diameter and accurate replication
  • Binding RNA polymerase during transcription
  • Providing the energy for polynucleotide synthesis

The specific base pairing (A-T with 2 H-bonds, G-C with 3 H-bonds) between a purine and a pyrimidine ensures the two DNA strands are equidistant apart, creating a uniform diameter. This complementarity is also the molecular logic for semi-conservative replication.

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