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nmdcat.online June 27, 2026

The fundamental difference between a nucleoside and a nucleotide is that a nucleotide contains a

A. Nitrogenous base linked to a sugar
B. Phosphate group esterified to the sugar
✓
C. Purine base instead of a pyrimidine base
D. Deoxyribose sugar instead of a ribose sugar

📝 Explanation

A nucleoside consists of a nitrogenous base plus a pentose sugar. A nucleotide is a nucleoside with one or more phosphate groups covalently bonded to the 5' carbon (or 3' carbon) of the sugar. The addition of phosphate is the defining difference.

📖 Additional Information

  • Nitrogenous base linked to a sugar
  • Phosphate group esterified to the sugar
  • Purine base instead of a pyrimidine base
  • Deoxyribose sugar instead of a ribose sugar

A nucleoside consists of a nitrogenous base plus a pentose sugar. A nucleotide is a nucleoside with one or more phosphate groups covalently bonded to the 5' carbon (or 3' carbon) of the sugar. The addition of phosphate is the defining difference.

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