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nmdcat.online June 27, 2026

The reason some enzymes are secreted as proenzymes (zymogens) is to

A. Increase the enzyme's catalytic rate once released
B. Prevent the enzyme from digesting the tissues where it is synthesized
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C. Allow the enzyme to function at a wider range of pH values
D. Target the enzyme to a specific location inside the cell

📝 Explanation

Zymogens like pepsinogen, trypsinogen, and chymotrypsinogen are inactive precursors of powerful proteases. They are activated by cleavage only after reaching the gut lumen. This prevents them from hydrolyzing the proteins of the cells that produce them, which would lead to tissue destruction.

📖 Additional Information

  • Increase the enzyme's catalytic rate once released
  • Prevent the enzyme from digesting the tissues where it is synthesized
  • Allow the enzyme to function at a wider range of pH values
  • Target the enzyme to a specific location inside the cell

Zymogens like pepsinogen, trypsinogen, and chymotrypsinogen are inactive precursors of powerful proteases. They are activated by cleavage only after reaching the gut lumen. This prevents them from hydrolyzing the proteins of the cells that produce them, which would lead to tissue destruction.

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