BIO NMDCAT Cytoplasmic Organelles
nmdcat.online July 4, 2026

13. The specific structure within the nuclear pore complex that acts as the central selective hydrogel barrier to free macromolecular diffusion is composed of

A. Rigid glycoprotein gates
B. Hydrophobic lipid patches
C. Phenylalanine-Glycine repeat domains
D. Charged carbohydrate chains

📝 Explanation

FG-nucleoporins (Phenylalanine-Glycine repeats) form a chaotic, flexible brush-like gel structure inside the pore that blocks large unchaperoned molecules.

📖 Additional Information

  • Rigid glycoprotein gates
  • Hydrophobic lipid patches
  • Phenylalanine-Glycine repeat domains
  • Charged carbohydrate chains

FG-nucleoporins (Phenylalanine-Glycine repeats) form a chaotic, flexible brush-like gel structure inside the pore that blocks large unchaperoned molecules.

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