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BIO NMDCAT Cytoplasmic Organelles
nmdcat.online July 4, 2026

27. The insertion of a nascent polypeptide chain into the lumen of the rough endoplasmic reticulum occurs co-translationally following recognition by the

A. KDEL receptor
B. Signal Recognition Particle
✓
C. Golgi anchor complex
D. Clathrin coat protein

📝 Explanation

The Signal Recognition Particle (SRP) binds the emerging N-terminal signal sequence of a peptide, stalling translation until it docks with the RER membrane.

📖 Additional Information

  • KDEL receptor
  • Signal Recognition Particle
  • Golgi anchor complex
  • Clathrin coat protein

The Signal Recognition Particle (SRP) binds the emerging N-terminal signal sequence of a peptide, stalling translation until it docks with the RER membrane.

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