BIO NMDCAT Cytoplasmic Organelles

nmdcat.online July 4, 2026

28. The retention of resident enzymatic proteins within the lumen of the endoplasmic reticulum is mediated by a specific C-terminal amino acid sequence known as the

A. NLS tag

B. M6P tag

C. KDEL sequence

✓

D. Ubiquitin tail

📝 Explanation

The Lys-Asp-Glu-Leu (KDEL) sequence at the C-terminus of ER-resident proteins ensures they are captured and recycled back if they escape to the Golgi.

📖 Additional Information

NLS tag
M6P tag
KDEL sequence
Ubiquitin tail

The Lys-Asp-Glu-Leu (KDEL) sequence at the C-terminus of ER-resident proteins ensures they are captured and recycled back if they escape to the Golgi.

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27. The insertion of a nascent polypeptide chain into the lumen of the rough endoplasmic reticulum occurs co-translationally following recognition by the

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