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BIO NMDCAT Cytoplasmic Organelles
nmdcat.online July 4, 2026

29. An accumulation of misfolded or unfolded proteins within the lumen of the rough endoplasmic reticulum triggers a protective cellular response designated as the

A. Apoptotic caspase cascade
B. Unfolded Protein Response
✓
C. Autophagic degradation pathway
D. Glycosylation arrest network

📝 Explanation

The Unfolded Protein Response (UPR) activates signaling loops to expand ER volume, increase chaperone expression, and halt translation to manage stress.

📖 Additional Information

  • Apoptotic caspase cascade
  • Unfolded Protein Response
  • Autophagic degradation pathway
  • Glycosylation arrest network

The Unfolded Protein Response (UPR) activates signaling loops to expand ER volume, increase chaperone expression, and halt translation to manage stress.

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