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BIO NMDCAT Cytoplasmic Organelles
nmdcat.online July 4, 2026

34. During the process of lipid synthesis in the smooth endoplasmic reticulum, the mechanism that ensures symmetric expansion of both leaflets of the bilayer is the action of

A. ATP-dependent flippases
B. ATP-independent scramblases
✓
C. Passive lipid diffusion pathways
D. Vesicular transport loops

📝 Explanation

New lipids are added to the cytosolic leaflet of the ER. Scramblases flip lipids randomly across leaflets without needing energy, balancing out the bilayer surface area.

📖 Additional Information

  • ATP-dependent flippases
  • ATP-independent scramblases
  • Passive lipid diffusion pathways
  • Vesicular transport loops

New lipids are added to the cytosolic leaflet of the ER. Scramblases flip lipids randomly across leaflets without needing energy, balancing out the bilayer surface area.

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