BIO NMDCAT Structure of DNA
nmdcat.online July 3, 2026

96. A genetic mutation introduces a premature termination codon (PTC) into the middle of a gene’s second exon. The eukaryotic cell identifies this aberrant transcript using a surveillance pathway that targets the mRNA for degradation before translation, a process known as

A. RNA interference (RNAi)
B. Nonsense-mediated mRNA decay (NMD)
C. Alternative splicing modulation
D. Epigenetic gene silencing

📝 Explanation

NMD is a surveillance mechanism that detects premature stop codons on transcripts and degrades them, preventing the accumulation of toxic, truncated proteins.

📖 Additional Information

  • RNA interference (RNAi)
  • Nonsense-mediated mRNA decay (NMD)
  • Alternative splicing modulation
  • Epigenetic gene silencing

NMD is a surveillance mechanism that detects premature stop codons on transcripts and degrades them, preventing the accumulation of toxic, truncated proteins.

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