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Practice Questions

A virus possessing an envelope usually enters host cells by

A. Binary fission
B. Fusion of its envelope with the host cell membrane
C. Conjugation
D. Sporulation

Enveloped viruses commonly enter cells by membrane fusion or receptor-mediated endocytosis.

nmdcat.online BIO by M Tahir ( Lecturer Al Azhar )
Jul 11, 2026

In host-based classification, Human Immunodeficiency Virus belongs to

A. Plant viruses
B. Animal viruses
C. Bacteriophages
D. Archaeal viruses

HIV infects human immune cells and therefore belongs to the animal viruses.

nmdcat.online BIO by M Tahir ( Lecturer Al Azhar )
Jul 11, 2026

The characteristic feature of complex viruses is the presence of

A. Only an icosahedral capsid
B. Both helical and icosahedral components with specialized structures
C. Only a lipid envelope
D. Only a circular RNA genome

Complex viruses, such as bacteriophage T4, possess an icosahedral head, helical tail, and specialized attachment structures.

nmdcat.online BIO by M Tahir ( Lecturer Al Azhar )
Jul 11, 2026

During classification based on genome type, Hepatitis C virus possesses

A. Double-stranded DNA
B. Single-stranded positive-sense RNA
C. Double-stranded RNA
D. Single-stranded DNA

Hepatitis C virus belongs to the Flaviviridae family and contains a positive-sense ssRNA genome.

nmdcat.online BIO by M Tahir ( Lecturer Al Azhar )
Jul 11, 2026

In the Baltimore classification system, retroviruses are placed in

A. Group IV
B. Group V
C. Group VI
D. Group VII

Retroviruses possess single-stranded RNA and use reverse transcriptase to synthesize DNA before replication. HIV is the best-known example.

nmdcat.online BIO by M Tahir ( Lecturer Al Azhar )
Jul 11, 2026

In classification based on disease, Rabies virus primarily affects the

A. Digestive system
B. Nervous system
C. Endocrine system
D. Urinary system

Rabies virus travels through peripheral nerves to the central nervous system, causing fatal encephalitis if untreated.

nmdcat.online BIO by M Tahir ( Lecturer Al Azhar )
Jul 11, 2026

Regarding plant viruses, the spread of infection commonly occurs through

A. Respiratory droplets
B. Insect vectors or mechanical injury
C. Airborne fungal spores only
D. Human blood transfusion

Most plant viruses enter through wounds or are transmitted by insect vectors such as aphids because intact plant cell walls prevent direct entry.

nmdcat.online BIO by M Tahir ( Lecturer Al Azhar )
Jul 11, 2026

The characteristic feature of bacteriophages that facilitates injection of nucleic acid into bacteria is the

A. Lipid envelope
B. Tail sheath and tail tube
C. Envelope glycoproteins
D. Ribosomal proteins

The contractile tail sheath helps inject viral DNA through the bacterial cell wall into the host cytoplasm.

nmdcat.online BIO by M Tahir ( Lecturer Al Azhar )
Jul 11, 2026

During classification based on envelope, viruses possessing lipid envelopes are generally more susceptible to

A. Drying and detergents
B. Ultraviolet radiation only
C. High atmospheric pressure
D. Mechanical shaking only

Lipid envelopes are easily disrupted by detergents, alcohol, and drying, resulting in loss of infectivity.

nmdcat.online BIO by M Tahir ( Lecturer Al Azhar )
Jul 11, 2026

The viral disease COVID-19 is caused by a member of the family possessing

A. Double-stranded DNA genome
B. Positive-sense single-stranded RNA genome
C. Double-stranded RNA genome
D. Single-stranded DNA genome

SARS-CoV-2 is an enveloped positive-sense single-stranded RNA virus belonging to the Coronaviridae family.

nmdcat.online BIO by M Tahir ( Lecturer Al Azhar )
Jul 11, 2026

During classification based on host range, viruses capable of infecting both humans and animals are commonly described as

A. Archaeal viruses
B. Zoonotic viruses
C. Plant viruses
D. Bacteriophages

Zoonotic viruses naturally circulate among animals but can also infect humans. Rabies virus and some coronaviruses are examples.

nmdcat.online BIO by M Tahir ( Lecturer Al Azhar )
Jul 11, 2026

According to structural classification, Adenovirus is best described as a

A. Naked icosahedral virus
B. Enveloped helical virus
C. Complex bacteriophage
D. Filamentous virus

Adenovirus lacks a lipid envelope and possesses an icosahedral protein capsid enclosing double-stranded DNA.

nmdcat.online BIO by M Tahir ( Lecturer Al Azhar )
Jul 11, 2026

A characteristic feature distinguishing RNA viruses from DNA viruses is that RNA viruses generally

A. Replicate only inside the nucleus
B. Exhibit a higher mutation rate
C. Always possess envelopes
D. Always infect plants

RNA polymerases lack efficient proofreading mechanisms, resulting in frequent mutations and rapid viral evolution.

nmdcat.online BIO by M Tahir ( Lecturer Al Azhar )
Jul 11, 2026

In viral classification, Herpes Simplex Virus belongs to the group of

A. Double-stranded DNA viruses
B. Double-stranded RNA viruses
C. Single-stranded DNA viruses
D. Positive-sense RNA viruses

Herpesviruses possess large linear double-stranded DNA genomes enclosed within an icosahedral capsid.

nmdcat.online BIO by M Tahir ( Lecturer Al Azhar )
Jul 11, 2026

During classification based on nucleic acid, a virus containing negative-sense single-stranded RNA requires

A. Direct translation by host ribosomes
B. Conversion into complementary positive-sense RNA before translation
C. DNA synthesis before infection
D. Reverse transcription immediately after entry

Negative-sense RNA cannot be translated directly. It must first be converted into positive-sense RNA by viral RNA-dependent RNA polymerase.

nmdcat.online BIO by M Tahir ( Lecturer Al Azhar )
Jul 11, 2026

During classification based on diseases, Human Papillomavirus (HPV) is primarily associated with

A. Liver infections
B. Skin and cervical infections
C. Respiratory tract infections
D. Gastrointestinal infections

Human Papillomavirus infects epithelial tissues and is responsible for warts and cervical cancer.

nmdcat.online BIO by M Tahir ( Lecturer Al Azhar )
Jul 11, 2026

An important characteristic distinguishing complex viruses from helical and icosahedral viruses is the presence of

A. Only a lipid envelope
B. Specialized structures such as head and tail
C. Double-stranded RNA only
D. Absence of capsid proteins

Complex viruses, particularly bacteriophages, possess specialized structures like heads, tails, and tail fibers for host attachment.

nmdcat.online BIO by M Tahir ( Lecturer Al Azhar )
Jul 11, 2026

During classification based on capsid symmetry, Tobacco Mosaic Virus belongs to the

A. Icosahedral group
B. Helical group
C. Complex group
D. Polyhedral-envelope group

TMV has a rod-shaped appearance due to its helical arrangement of capsid proteins around the RNA genome.

nmdcat.online BIO by M Tahir ( Lecturer Al Azhar )
Jul 11, 2026

Regarding coronavirus, the viral genome consists of

A. Double-stranded DNA
B. Single-stranded positive-sense RNA
C. Double-stranded RNA
D. Single-stranded DNA

Coronaviruses possess one of the largest positive-sense single-stranded RNA genomes among viruses.

nmdcat.online BIO by M Tahir ( Lecturer Al Azhar )
Jul 11, 2026
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