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nmdcat.online July 28, 2026

During a laboratory experiment, a tissue sample is placed in a calcium-free extracellular fluid. Upon electrical stimulation, the tissue completely fails to contract, whereas another tissue sample continues to contract for a short period before failing. The first tissue most likely belongs to which type of muscle?

A. Skeletal muscle
B. Cardiac muscle
C. Smooth muscle
✓
D. Striated voluntary muscle

📝 Explanation

Smooth muscle relies heavily on the influx of extracellular calcium for contraction, whereas skeletal muscle relies almost exclusively on intracellular calcium stored in the sarcoplasmic reticulum. Cardiac muscle requires both, but smooth muscle is most immediately affected by the lack of extracellular calcium.

📖 Additional Information

  • Skeletal muscle
  • Cardiac muscle
  • Smooth muscle
  • Striated voluntary muscle

Smooth muscle relies heavily on the influx of extracellular calcium for contraction, whereas skeletal muscle relies almost exclusively on intracellular calcium stored in the sarcoplasmic reticulum. Cardiac muscle requires both, but smooth muscle is most immediately affected by the lack of extracellular calcium.

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