MCQs
10982 questions found
A.
Change its own stereochemistry
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B.
Produce racemic products
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C.
Distinguish between optical isomers and act on only one
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D.
Convert every substrate into its optical isomer
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A.
Its coenzyme works only at low pH
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B.
Catalytic residues require a specific protonation state
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C.
The substrate is active only at pH 2
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D.
Product inhibition occurs at higher pH
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A.
Lowest activation energy
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B.
Highest activation energy
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C.
Greatest entropy change
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D.
Largest number of water molecules
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A.
Quaternary structure
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B.
Amino acid side chains arranged in the active site
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A.
Random substrate binding
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B.
Both substrates bind before any product is released, in a compulsory order
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C.
Product leaves before all substrates bind
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D.
Reaction rate is independent of the second substrate
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A.
A completely uniform charge distribution
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B.
A significantly lowered dielectric constant that enhances electrostatic interactions
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C.
A pH always equal to 7.0
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D.
An unlimited supply of free water molecules
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A.
Competitive reversible inhibition
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B.
Non competitive reversible inhibition
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C.
Irreversible suicide inhibition
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D.
Allosteric regulation
✓
A.
Sulfhydryl group in its thiolate (S?) form
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A.
Competitive inhibition
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B.
Non competitive inhibition
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C.
Uncompetitive inhibition
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D.
Irreversible inhibition
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A.
Directly break substrate bonds
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B.
Increase activation energy
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C.
Lower activation energy by stabilizing the transition state
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D.
Dissociate the enzyme cofactor complex
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B.
Histidine acting as a general base
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C.
Aspartate donating a proton
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D.
Formation of a disulfide bond
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A.
Denaturing the substrate
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B.
Binding two substrates close together to increase their effective concentration
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C.
Lowering the pH of the solution
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D.
Using a metal ion to generate hydroxyl radicals
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A.
Release of the unaltered second substrate
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B.
Binding of a water molecule and its nucleophilic attack on the acyl enzyme intermediate
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C.
Binding of an allosteric inhibitor
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D.
Auto degradation of the enzyme
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A.
Sequential ordered mechanism
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B.
Sequential random mechanism
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C.
Ping pong double displacement mechanism
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D.
Concerted acid base mechanism
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A.
Substrate inhibits product
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B.
One product is released before all substrates bind
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C.
Cooperative binding occurs
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D.
Non competitive inhibition occurs
✓