MCQs

11212 questions found

Practice Questions

A patient with an autoimmune disease, Systemic Lupus Erythematosus (SLE), experiences damage to multiple organs. SLE is characterized by the production of:

A. Autoantibodies that attack the body's own tissues.
B. Increased complement proteins.
C. Decreased inflammatory mediators.
D. Excessive B-cell suppression.
nmdcat.online BS Nursing
Jun 6, 2026

A patient with a long history of smoking develops emphysema, a form of COPD. The primary pathological change in emphysema is:

A. Bronchial smooth muscle hypertrophy.
B. Alveolar wall destruction and loss of elastic recoil.
C. Reversible airway inflammation.
D. Increased mucus gland hyperplasia.
nmdcat.online BS Nursing
Jun 6, 2026

A patient with severe sepsis develops disseminated intravascular coagulation (DIC). The key pathophysiological feature of DIC is:

A. Excessive clot formation leading to widespread microvascular thrombosis and consumption of clotting factors, followed by bleeding.
B. Only excessive bleeding with no clot formation.
C. Increased production of platelets.
D. Decreased fibrinolysis.
nmdcat.online BS Nursing
Jun 6, 2026

A patient with a genetic disorder has two copies of the abnormal gene on non-sex chromosomes to manifest the disease. This inheritance pattern is:

A. Autosomal dominant.
B. Autosomal recessive.
C. X-linked dominant.
D. X-linked recessive.
nmdcat.online BS Nursing
Jun 6, 2026

A patient with a severe burn injury develops massive edema in the affected area. This is primarily due to:

A. Increased intravascular protein synthesis.
B. Decreased capillary permeability.
C. Increased capillary hydrostatic pressure and increased capillary permeability.
D. Decreased lymphatic drainage.
nmdcat.online BS Nursing
Jun 6, 2026

A patient with asthma experiences an acute exacerbation. The primary pathophysiological changes in the airways during an asthma attack include:

A. Bronchial smooth muscle relaxation and decreased mucus production.
B. Bronchospasm, airway inflammation, and increased mucus production.
C. Destruction of alveolar walls.
D. Fluid accumulation in the pleural space.
nmdcat.online BS Nursing
Jun 6, 2026

A patient with a stroke is diagnosed with an ischemic stroke. The primary pathophysiological event causing this type of stroke is:

A. Rupture of a cerebral blood vessel.
B. An embolus or thrombus obstructing cerebral blood flow.
C. Vasospasm of cerebral arteries.
D. Hypoxia due to respiratory failure.
nmdcat.online BS Nursing
Jun 6, 2026

Type 1 diabetes mellitus is characterized by the autoimmune destruction of which cells in the pancreas?

A. Alpha cells.
B. Beta cells.
C. Delta cells.
D. Acinar cells.
nmdcat.online BS Nursing
Jun 6, 2026

A patient experiences severe vomiting and diarrhea. The nurse anticipates the development of which acid-base imbalance?

A. Respiratory acidosis.
B. Metabolic acidosis.
C. Respiratory alkalosis.
D. Metabolic alkalosis.
nmdcat.online BS Nursing
Jun 6, 2026

In the process of carcinogenesis, “initiation” refers to:

A. The rapid proliferation of genetically altered cells.
B. The irreversible genetic alteration of a cell by a carcinogen.
C. The spread of cancer cells to distant sites.
D. The formation of a visible tumor.
nmdcat.online BS Nursing
Jun 6, 2026

A patient develops a tumor that is encapsulated, well-differentiated, and does not metastasize. This describes a:

A. Malignant tumor.
B. Benign tumor.
C. Carcinoma in situ.
D. Sarcoma.
nmdcat.online BS Nursing
Jun 6, 2026

A patient with a traumatic brain injury develops Syndrome of Inappropriate Antidiuretic Hormone (SIADH). This results in:

A. Increased urine output and hypernatremia.
B. Decreased urine output and hyponatremia.
C. Normal fluid balance with hyperkalemia.
D. Fluid volume deficit and hypercalcemia.
nmdcat.online BS Nursing
Jun 6, 2026

A patient with a history of alcohol abuse develops liver cirrhosis. The pathological changes seen in cirrhosis are primarily characterized by:

A. Fatty infiltration with normal liver architecture.
B. Widespread fibrosis and nodule formation, disrupting liver structure and function.
C. Acute inflammation with viral replication.
D. Increased bile production.
nmdcat.online BS Nursing
Jun 6, 2026

A patient with prolonged immobility develops a pressure injury. The primary mechanism of tissue damage in pressure injuries is:

A. Direct bacterial infection.
B. Friction and shear forces causing tissue deformation and ischemia.
C. Allergic reaction to bedding material.
D. Excessive moisture leading to maceration.
nmdcat.online BS Nursing
Jun 6, 2026

A patient with a severe bacterial infection develops systemic inflammatory response syndrome (SIRS) and then progresses to septic shock. The key pathophysiological event in septic shock is:

A. Massive vasodilation and increased capillary permeability due to inflammatory mediators.
B. Direct myocardial tissue damage.
C. Pulmonary embolism.
D. Hyperglycemia due to insulin resistance.
nmdcat.online BS Nursing
Jun 6, 2026

A patient with chronic kidney disease (CKD) develops anemia. The most common pathophysiological reason for this is:

A. Increased red blood cell destruction.
B. Decreased iron absorption in the gut.
C. Impaired production of erythropoietin by the kidneys.
D. Excessive blood loss through dialysis.
nmdcat.online BS Nursing
Jun 6, 2026

A patient experiences a sudden onset of chest pain described as “crushing” and radiating to the left arm. This pain is caused by myocardial ischemia, which is a result of:

A. Decreased oxygen demand by the heart.
B. Inadequate oxygen supply to the myocardium.
C. Increased venous return to the heart.
D. Pulmonary hypertension.
nmdcat.online BS Nursing
Jun 6, 2026

During the inflammatory response, the primary purpose of vasodilation is to:

A. Decrease blood flow to the injured area.
B. Reduce capillary permeability.
C. Increase blood flow to the injured area, facilitating delivery of immune cells.
D. Constrict arterioles to limit swelling.
nmdcat.online BS Nursing
Jun 6, 2026

A patient with uncontrolled diabetes mellitus develops diabetic ketoacidosis (DKA). The primary underlying pathophysiological mechanism of DKA is:

A. Excessive insulin production leading to hypoglycemia.
B. Absolute or relative insulin deficiency leading to increased fat metabolism and ketone body formation.
C. Excessive fluid intake leading to hyponatremia.
D. Increased renal excretion of glucose without ketone production.
nmdcat.online BS Nursing
Jun 6, 2026
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