Practice Questions

49. A patient with newly diagnosed Type 2 Diabetes Mellitus has elevated fasting blood glucose and insulin resistance. What is the technical pathophysiological defect primarily responsible for insulin resistance?

A. Autoimmune destruction of pancreatic beta cells.
B. Decreased insulin production.
C. Impaired cellular response to insulin, leading to inadequate glucose uptake by peripheral tissues.
D. Excess glucagon secretion.
nmdcat.online BS Nursing
Jun 6, 2026

47. A patient with untreated hypertension develops left ventricular hypertrophy. What is the technical pathophysiological consequence of long-standing hypertension on the heart?

A. Dilation of the left ventricle.
B. Increased afterload, leading to compensatory hypertrophy of the left ventricle.
C. Valvular stenosis.
D. Increased cardiac output.
nmdcat.online BS Nursing
Jun 6, 2026

46. A patient with chronic bronchitis is characterized by a “blue bloater” appearance (cyanosis, edema). What is the technical primary pathophysiological cause of these features?

A. Alveolar destruction and air trapping.
B. Chronic inflammation of the bronchi, leading to mucus hypersecretion, airway obstruction, and hypoxemia/hypercapnia.
C. Reversible bronchospasm.
D. Pulmonary fibrosis.
nmdcat.online BS Nursing
Jun 6, 2026

45. A patient with severe sepsis develops disseminated intravascular coagulation (DIC). What is the critical clinical urgency in managing DIC?

A. Administering large volumes of intravenous fluids.
B. Promptly treating the underlying cause of sepsis and managing bleeding/thrombosis.
C. Performing immediate surgery.
D. Providing only symptomatic relief.
nmdcat.online BS Nursing
Jun 6, 2026

43. A patient with acute myocardial infarction (MI) is given aspirin. From a medicinal perspective, what is the technical pathophysiological mechanism of aspirin in this context?

A. Increases blood pressure.
B. Inhibits platelet aggregation and thrombus formation.
C. Directly dilates coronary arteries.
D. Increases myocardial contractility.
nmdcat.online BS Nursing
Jun 6, 2026

42. A patient with osteoarthiritis experiences joint pain and stiffness, especially with movement, worsening over the day. From a technical pathophysiological perspective, osteoarthritis is characterized by:

A. Autoimmune inflammation of the synovial membrane.
B. Degeneration of articular cartilage.
C. Deposition of uric acid crystals.
D. Bacterial infection of the joint.
nmdcat.online BS Nursing
Jun 6, 2026

41. A patient with liver cirrhosis develops hepatic encephalopathy, characterized by confusion, asterixis, and altered mental status. What is the technical primary pathophysiological mechanism causing this complication?

A. Accumulation of glucose in the brain.
B. Impaired detoxification of ammonia and other neurotoxins by the liver.
C. Cerebral ischemia.
D. Electrolyte imbalance.
nmdcat.online BS Nursing
Jun 6, 2026

40. A patient with acute kidney injury develops hyperkalemia. What is the urgent clinical concern and critical pathophysiological consequence of severe hyperkalemia?

A. Hypoglycemia.
B. Cardiac arrhythmias and potential cardiac arrest.
C. Hypotension.
D. Metabolic alkalosis.
nmdcat.online BS Nursing
Jun 6, 2026
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