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nmdcat.online July 28, 2026

A medical relevance of understanding muscle tissue differences is the development of calcium channel blockers. These drugs are primarily used to treat hypertension (high blood pressure) and angina. They exert their biological effect mainly by acting on:

A. Skeletal and cardiac muscle
B. Smooth and skeletal muscle
C. Cardiac and vascular smooth muscle
✓
D. Only vascular smooth muscle

📝 Explanation

Calcium channel blockers prevent the influx of extracellular calcium. Since both cardiac muscle and vascular smooth muscle rely heavily on extracellular calcium for contraction, these drugs decrease heart rate/contractility and cause vasodilation, effectively lowering blood pressure and reducing heart strain.

📖 Additional Information

  • Skeletal and cardiac muscle
  • Smooth and skeletal muscle
  • Cardiac and vascular smooth muscle
  • Only vascular smooth muscle

Calcium channel blockers prevent the influx of extracellular calcium. Since both cardiac muscle and vascular smooth muscle rely heavily on extracellular calcium for contraction, these drugs decrease heart rate/contractility and cause vasodilation, effectively lowering blood pressure and reducing heart strain.

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