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nmdcat.online July 28, 2026

During the process of cell differentiation, which muscle type loses its ability to divide and form new cells almost completely, relying solely on hypertrophy for growth?

A. Both skeletal and smooth muscle
B. Smooth muscle only
C. Cardiac muscle only
✓
D. Skeletal muscle only

📝 Explanation

Mature cardiac muscle cells (cardiomyocytes) are terminally differentiated and generally lose their ability to divide. Skeletal muscle cannot divide but has satellite cells for limited repair. Smooth muscle retains a significant capacity to divide and regenerate (hyperplasia).

📖 Additional Information

  • Both skeletal and smooth muscle
  • Smooth muscle only
  • Cardiac muscle only
  • Skeletal muscle only

Mature cardiac muscle cells (cardiomyocytes) are terminally differentiated and generally lose their ability to divide. Skeletal muscle cannot divide but has satellite cells for limited repair. Smooth muscle retains a significant capacity to divide and regenerate (hyperplasia).

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