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Practice Questions

Correct: Collagen provides tensile strength and flexibility. Without it, bone becomes brittle. A: Rigidity depends mainly on minerals. C: Minerals are stored in the matrix. D: Osteons are structural units, not formed by collagen alone. Concept: Organic matrix of bone.

nmdcat.online BIO NMDCAT
Jul 27, 2026

Which characteristic is common to both cartilage and bone?

A. Presence of Haversian canals
B. Rich blood supply
C. Cells embedded in an extracellular matrix ✓
D. High concentration of elastic fibers

Correct: Both tissues are connective tissues with cells embedded in a matrix. A: Only bone has Haversian canals. B: Cartilage is avascular. D: Elastic fibers are mainly found in elastic cartilage. Concept: Comparison of connective tissues.

nmdcat.online BIO NMDCAT
Jul 27, 2026

During an experiment, equal forces are applied to a bone and a cartilage sample. The cartilage bends while the bone remains rigid. The difference is mainly due to the:

A. Presence of collagen only in cartilage
B. Greater mineral content of bone ✓
C. Presence of osteocytes in cartilage
D. Absence of matrix in cartilage

Correct: Bone contains abundant calcium salts that provide rigidity. A: Both tissues contain collagen. C: Osteocytes are bone cells. D: Cartilage has a well-developed matrix. Concept: Mechanical properties of bone and cartilage.

nmdcat.online BIO NMDCAT
Jul 27, 2026

If osteoclast activity greatly exceeds osteoblast activity over a prolonged period, the most likely outcome is:

A. Increased bone density
B. Reduced bone mass and increased fracture risk ✓
C. Excess cartilage formation
D. Increased muscle strength

Correct: Osteoclasts resorb bone; excessive activity weakens bones. A: Bone density decreases. C: Osteoclasts do not form cartilage. D: Muscle strength is unrelated. Concept: Bone remodeling.

nmdcat.online BIO NMDCAT
Jul 27, 2026

A patient suffers degeneration of cartilage covering the ends of bones. Which consequence is most likely during movement?

A. Increased production of bone marrow
B. Increased friction between bones ✓
C. Increased calcium storage
D. Increased bone flexibility

Correct: Loss of articular cartilage increases friction, causing pain and restricted movement. A: Bone marrow production is unrelated. C: Calcium storage is unaffected. D: Bone flexibility does not increase. Concept: Function of articular cartilage.

nmdcat.online BIO NMDCAT
Jul 27, 2026

During microscopic examination, a tissue contains concentric lamellae surrounding a central canal. The tissue is identified as:

A. Elastic cartilage
B. Hyaline cartilage
C. Compact bone ✓
D. Fibrocartilage

Correct: Compact bone consists of osteons with concentric lamellae around Haversian canals. A, B & D: Cartilage lacks osteons and Haversian canals. Concept: Histology of compact bone.

nmdcat.online BIO NMDCAT
Jul 27, 2026

A surgeon removes the periosteum from part of a bone. Which function of the bone is most likely to be affected first?

A. Production of blood cells
B. Increase in bone thickness and repair ✓
C. Storage of calcium salts
D. Protection of internal organs

Correct: The periosteum contains osteoblasts responsible for appositional growth and fracture repair. A: Blood cells are produced in bone marrow. C: Mineral storage continues in existing bone. D: Protection remains unless bone is damaged. Concept: Role of periosteum.

nmdcat.online BIO NMDCAT
Jul 27, 2026

Compared with compact bone, cartilage is better suited to absorb compressive forces because its matrix is:

A. Highly mineralized
B. Flexible and rich in chondrin ✓
C. Organized into osteons
D. Richly supplied with blood vessels

Correct: Chondrin gives cartilage resilience and flexibility for shock absorption. A: Mineralization makes bone rigid. C: Osteons are bone structures. D: Cartilage is avascular. Concept: Structure-function relationship of cartilage.

nmdcat.online BIO NMDCAT
Jul 27, 2026

During growth, a child’s long bones increase in diameter mainly due to the activity of:

A. Chondrocytes of epiphyseal plate
B. Osteoblasts beneath the periosteum ✓
C. Osteoclasts in the medullary cavity
D. Osteocytes within lacunae

Correct: Osteoblasts beneath the periosteum deposit new bone on the outer surface, increasing bone thickness. A: Chondrocytes increase bone length. C: Osteoclasts resorb bone. D: Osteocytes mainly maintain bone tissue. Concept: Appositional growth of bone.

nmdcat.online BIO NMDCAT
Jul 27, 2026

Which statement best explains why bone is considered a living tissue?

A. It is composed entirely of mineral salts
B. It contains living cells supplied by blood vessels ✓
C. It lacks extracellular matrix
D. It cannot repair after injury

Correct: Bone contains living osteocytes, blood vessels, and nerves, making it metabolically active. A: Minerals alone are non-living. C: Bone has abundant extracellular matrix. D: Bone has a remarkable capacity for repair. Concept: Characteristics of living bone tissue.

nmdcat.online BIO NMDCAT
Jul 27, 2026

During laboratory analysis, removal of collagen fibers from a bone leaves it hard but easily broken. This finding shows that collagen primarily provides:

A. Bone hardness
B. Bone elasticity and tensile strength ✓
C. Bone mineral storage
D. Blood cell production

Correct: Collagen gives bones flexibility and resistance to breaking. A: Hardness is due to mineral salts. C: Minerals are stored in bone, not collagen. D: Blood cells are produced in bone marrow. Concept: Role of collagen in bone.

nmdcat.online BIO NMDCAT
Jul 27, 2026

An athlete experiences smooth movement at the knee joint despite repeated motion. This is mainly due to articular cartilage, which functions to:

A. Produce red blood cells
B. Reduce friction and absorb shock ✓
C. Attach muscles to bones
D. Store phosphorus only

Correct: Articular cartilage provides a smooth, shock-absorbing surface at joints. A: Red blood cells are produced in bone marrow. C: Tendons attach muscles to bones. D: Mineral storage is mainly a function of bone. Concept: Function of articular cartilage.

nmdcat.online BIO NMDCAT
Jul 27, 2026

A student compares cartilage and bone under the microscope. Which observation correctly identifies cartilage?

A. Presence of Haversian canals
B. Presence of osteocytes in concentric rings
C. Chondrocytes enclosed in lacunae without Haversian canals ✓
D. Numerous blood vessels surrounding cells

Correct: Cartilage contains chondrocytes in lacunae and lacks Haversian systems. A & B: These are features of compact bone. D: Cartilage is avascular. Concept: Microscopic comparison of cartilage and bone.

nmdcat.online BIO NMDCAT
Jul 27, 2026

During growth, cartilage present at the epiphyseal plate is gradually replaced by bone. This process is known as:

A. Calcification
B. Ossification ✓
C. Resorption
D. Mineralization

Correct: Ossification is the formation of bone tissue from cartilage. A & D: Calcification and mineralization are parts of ossification but not the complete process. C: Resorption refers to bone breakdown. Concept: Bone development.

nmdcat.online BIO NMDCAT
Jul 27, 2026

A fracture heals more rapidly than damage to the ear cartilage because bone contains:

A. Elastic cartilage
B. Blood vessels and osteoblasts ✓
C. Chondrocytes only
D. Dense regular connective tissue

Correct: Blood vessels supply nutrients, while osteoblasts produce new bone during healing. A: Elastic cartilage is found in the ear. C: Chondrocytes are cartilage cells. D: Dense connective tissue forms tendons and ligaments. Concept: Bone repair.

nmdcat.online BIO NMDCAT
Jul 27, 2026

Which feature allows compact bone to withstand heavy compressive forces more effectively than cartilage?

A. Presence of chondrin
B. Arrangement into osteons with mineralized matrix ✓
C. Lack of extracellular matrix
D. Presence of elastic fibers only

Correct: Compact bone consists of osteons and a mineralized matrix that provides great strength. A: Chondrin is found in cartilage. C: Bone has abundant extracellular matrix. D: Elastic fibers increase flexibility, not compressive strength. Concept: Structure of compact bone.

nmdcat.online BIO NMDCAT
Jul 27, 2026

Compared with skeletal muscle, cartilage is less capable of rapid repair because cartilage:

A. Contains fewer cells
B. Lacks blood vessels ✓
C. Contains collagen fibers
D. Has extracellular matrix

Correct: Cartilage heals slowly due to the absence of blood vessels. A: Cell number is not the primary reason. C & D: Both tissues contain connective elements but differ in vascularity. Concept: Healing of cartilage.

nmdcat.online BIO NMDCAT
Jul 27, 2026

A child with vitamin D deficiency develops soft and weak bones because vitamin D primarily promotes:

A. Collagen synthesis
B. Calcium absorption from the intestine ✓
C. Cartilage formation
D. Muscle contraction

Correct: Vitamin D enhances calcium absorption, essential for bone mineralization. A: Collagen synthesis is not its primary role. C: Cartilage formation is unaffected directly. D: Muscle contraction depends mainly on calcium availability, not vitamin D directly. Concept: Bone mineralization.

nmdcat.online BIO NMDCAT
Jul 27, 2026

Correct: Acid dissolves mineral salts, leaving collagen fibers that provide flexibility. A & B: These mineral salts are removed by acid. D: Bone marrow does not maintain bone shape. Concept: Organic and inorganic components of bone.

nmdcat.online BIO NMDCAT
Jul 27, 2026
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