Practice Questions

82. The molecular weight of a gene is determined directly by the

A. Number of lipid layers surrounding the chromosome
B. Total number of nucleotide base pairs making up its sequence
C. Concentration of amino acids stored in the cell nucleus
D. Number of ribosomes attached to its promoter

The mass of a gene depends on its length; longer nucleotide sequences contain more base pairs, increasing the total molecular weight.

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Enhancers are regulatory DNA sequences that bind activator proteins, interacting with the promoter to boost transcription.

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80. The dynamic structural property that describes the right-handed twisting of the two strands around a shared central axis is a

A. Helical configuration
B. Linear lattice topology
C. Planar crystalline matrix
D. Branched micellar loop

The Watson-Crick model shows DNA as a right-handed double helix, where two complementary strands twist around a central longitudinal axis.

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79. The molecular consequence of a mutation that introduces a stop codon near the beginning of a gene’s coding region is

A. The production of a completely normal protein product
B. The generation of a truncated, likely non-functional protein
C. Accelerated transcription of the entire gene locus
D. Spontaneous duplication of the mutated chromosome

A premature stop codon halts translation early, yielding an incomplete, truncated polypeptide chain that is usually non-functional.

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78. The physical structure of a chromosome in eukaryotic cells is formed when a single, massive molecule of double-stranded DNA is

A. Dissolved completely into a solution of lipids
B. Coiled and packed systematically with structural proteins
C. Broken into hundreds of short single-stranded RNA fragments
D. Linked covalently to the carbohydrate cell wall ribbon

Eukaryotic chromosomes are highly organized nucleoprotein complexes made of a single linear DNA molecule wound around structural histones.

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Electrostatic hydrogen bonds form between the partially positive hydrogen atoms and partially negative oxygen or nitrogen atoms of matching bases.

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76. The alteration of a single nucleotide base pair that has no effect on the target protein’s final amino acid sequence is a

A. Missense mutation
B. Silent mutation
C. Nonsense mutation
D. Frameshift mutation

Silent mutations alter the codon sequence without changing the translated amino acid, leaving the protein's function uncompromised.

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The terminator is a distinct downstream regulatory sequence that signals RNA polymerase to stop transcription and detach.

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74. The observation that the genetic code is universal across almost all living organisms implies that a human gene

A. Cannot function if inserted into a bacterial genome
B. Can be successfully transcribed and translated inside a bacterial cell
C. Uses completely different nitrogenous bases than a bacterial gene
D. Codes for lipids when expressed inside a prokaryotic host

Because the genetic code is nearly universal, organisms share the same codon-to-amino acid rules, making recombinant DNA tech possible.

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Ribosomes serve as the structural and catalytic factories where tRNA molecules match codons to assemble amino acids into a protein.

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