Practice Questions

Substrate binding induces conformational changes that optimize catalysis.

Myoglobin has a high oxygen affinity and releases oxygen only at low oxygen tension.

pI = (2.34 + 9.60)/2 = 5.97.

Hydroxyproline stabilizes the collagen triple helix through hydrogen bonding.

Tryptophan and tyrosine absorb ultraviolet light strongly near 280 nm.

RNase A spontaneously refolded after denaturation, proving sequence determines structure.

Hydrophobic residues at heptad repeat positions interlock to stabilize the coiled-coil.

Amphipathic helices possess hydrophobic and hydrophilic faces suited for membrane environments.

Domains are independently folded structural units within one polypeptide.

Burying hydrophobic residues releases ordered water molecules, increasing entropy.