Practice Questions

130. A patient with an acute asthma exacerbation presents with “pulsus paradoxus” (a decrease in systolic blood pressure during inspiration). What is the critical clinical urgency in assessing this sign?

A. It indicates a mild exacerbation.
B. It signifies severe airway obstruction and impending respiratory failure.
C. It suggests cardiac tamponade.
D. It is a normal physiological response.
nmdcat.online BS Nursing
Jun 6, 2026

129. A patient with severe heart failure is prescribed digoxin. From a medicinal perspective, what is the technical pathophysiological mechanism of digoxin?

A. Increases heart rate.
B. Inhibits Na+/K+-ATPase, increasing intracellular calcium and myocardial contractility (positive inotropy).
C. Directly dilates blood vessels.
D. Decreases preload.
nmdcat.online BS Nursing
Jun 6, 2026

128. A patient with a history of alcohol abuse develops Wernicke-Korsakoff syndrome. What is the technical primary pathophysiological deficiency?

A. Vitamin C deficiency.
B. Thiamine (Vitamin B1) deficiency.
C. Vitamin B12 deficiency.
D. Folic acid deficiency.
nmdcat.online BS Nursing
Jun 6, 2026

127. A patient with chronic obstructive pulmonary disease (COPD) develops pulmonary hypertension. What is the technical primary pathophysiological mechanism?

A. Increased production of surfactant.
B. Chronic hypoxemia leading to pulmonary vasoconstriction and vascular remodeling.
C. Decreased pulmonary blood flow.
D. Bronchospasm.
nmdcat.online BS Nursing
Jun 6, 2026

126. A patient with Type 1 Diabetes Mellitus has diabetic nephropathy. What is the technical primary pathophysiological change in the kidney?

A. Acute tubular necrosis.
B. Glomerulosclerosis (fibrosis and scarring of the glomeruli).
C. Renal artery stenosis.
D. Kidney stones.
nmdcat.online BS Nursing
Jun 6, 2026

125. A patient with a history of deep vein thrombosis (DVT) on anticoagulation develops sudden onset of abdominal pain and hematochezia. What is the critical clinical concern?

A. Appendicitis.
B. Anticoagulant-associated gastrointestinal bleeding.
C. Diverticulitis.
D. Irritable bowel syndrome.
nmdcat.online BS Nursing
Jun 6, 2026

124. A patient with chronic kidney disease (CKD) develops fluid overload. What is the technical primary pathophysiological reason for this?

A. Increased renal filtration.
B. Impaired renal excretion of sodium and water.
C. Decreased fluid intake.
D. Increased protein intake.
nmdcat.online BS Nursing
Jun 6, 2026

123. A patient with an acute stroke presents within the thrombolytic window. What is the critical clinical urgency for medicinal intervention if no contraindications exist?

A. To delay treatment until full recovery.
B. Immediate assessment for eligibility for thrombolytic therapy (tPA) to restore blood flow and minimize brain damage.
C. To administer antiplatelet agents only.
D. To observe and monitor.
nmdcat.online BS Nursing
Jun 6, 2026

122. A patient with chronic heart failure experiences cardiac remodeling (ventricular hypertrophy and dilation). What is the technical pathophysiological consequence of this remodeling on cardiac function?

A. Improved cardiac output.
B. Increased myocardial oxygen demand and impaired contractility, leading to progressive worsening of heart failure.
C. Decreased preload.
D. Enhanced relaxation.
nmdcat.online BS Nursing
Jun 6, 2026

121. A patient with a history of Gout experiences acute joint pain, swelling, and redness in the big toe. What is the technical primary pathophysiological mechanism of gout?

A. Autoimmune inflammation.
B. Deposition of uric acid crystals in the joint, leading to an inflammatory response.
C. Bacterial infection.
D. Degeneration of articular cartilage.
nmdcat.online BS Nursing
Jun 6, 2026
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