BIO NMDCAT Conjugated molecules

nmdcat.online July 3, 2026

18. A genetic defect that prevents the addition of mannose-6-phosphate to targeted glycoproteins in the Golgi apparatus will disrupt the

A. Synthesis of ATP in mitochondria

B. Delivery of structural enzymes to lysosomes

✓

C. Replication of nuclear DNA sequences

D. Secretion of insulin into the blood

📝 Explanation

Mannose-6-phosphate serves as a specific molecular sorting signal that targets newly synthesized hydrolytic enzymes to the lysosomes.

📖 Additional Information

Synthesis of ATP in mitochondria
Delivery of structural enzymes to lysosomes
Replication of nuclear DNA sequences
Secretion of insulin into the blood

Mannose-6-phosphate serves as a specific molecular sorting signal that targets newly synthesized hydrolytic enzymes to the lysosomes.

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