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BIO NMDCAT Structure of DNA
nmdcat.online July 3, 2026

18. The major and minor grooves observed along the exterior surface of the DNA double helix are structurally caused by

A. The presence of modified ribose sugars
B. The asymmetric attachment of base pairs to the sugar-phosphate backbones
✓
C. Spontaneous strand breaks in the phosphate chain
D. The attachment of regulatory histone proteins

📝 Explanation

The glycosidic bonds do not project directly opposite one another, making the spaces between the backbones unequal around the cylinder.

📖 Additional Information

  • The presence of modified ribose sugars
  • The asymmetric attachment of base pairs to the sugar-phosphate backbones
  • Spontaneous strand breaks in the phosphate chain
  • The attachment of regulatory histone proteins

The glycosidic bonds do not project directly opposite one another, making the spaces between the backbones unequal around the cylinder.

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