BIO NMDCAT Conjugated molecules

nmdcat.online July 3, 2026

21. The biochemical reason why nucleoproteins like chromosomes migrate toward the positive anode during gel electrophoresis is the

A. Basic nature of the histone core proteins

B. Negative charge of the phosphate groups on the associated DNA

✓

C. Presence of neutral carbohydrate markers

D. Hydrophobic nature of the nuclear membrane

📝 Explanation

Even when bound to basic proteins, the dense phosphate backbone of the DNA molecule provides a strong net negative charge to chromatin.

📖 Additional Information

Basic nature of the histone core proteins
Negative charge of the phosphate groups on the associated DNA
Presence of neutral carbohydrate markers
Hydrophobic nature of the nuclear membrane

Even when bound to basic proteins, the dense phosphate backbone of the DNA molecule provides a strong net negative charge to chromatin.

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