BIO NMDCAT Conjugated molecules
nmdcat.online July 3, 2026

41. The architectural arrangement of eukaryotic chromatin reveals that the interaction between DNA and histone proteins is primarily driven by

A. Covalent peptide linkage
B. Electrostatic attraction between opposite charges
C. Hydrophobic exclusion principles
D. Sharing of electrons between aromatic rings

📝 Explanation

Positively charged basic amino acids (lysine and arginine) on histones bind strongly to the negatively charged phosphates of the DNA molecule.

📖 Additional Information

  • Covalent peptide linkage
  • Electrostatic attraction between opposite charges
  • Hydrophobic exclusion principles
  • Sharing of electrons between aromatic rings

Positively charged basic amino acids (lysine and arginine) on histones bind strongly to the negatively charged phosphates of the DNA molecule.

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