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BIO NMDCAT Ribonucleic acid (RNA)
nmdcat.online July 3, 2026

43. The 3D L-shaped tertiary conformation of a transfer RNA (tRNA) molecule is primarily maintained by

A. Coiling around histone proteins
B. Hydrophobic stacking and tertiary hydrogen bonds
✓
C. Disulfide linkages between nucleotides
D. Covalent bonds between variable loops

📝 Explanation

While the 2D layout is a cloverleaf, the functional 3D conformation is an L-shape stabilized by complex non-Watson-Crick hydrogen bonding.

📖 Additional Information

  • Coiling around histone proteins
  • Hydrophobic stacking and tertiary hydrogen bonds
  • Disulfide linkages between nucleotides
  • Covalent bonds between variable loops

While the 2D layout is a cloverleaf, the functional 3D conformation is an L-shape stabilized by complex non-Watson-Crick hydrogen bonding.

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