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BIO NMDCAT Conjugated molecules
nmdcat.online July 3, 2026

44. The modification of chromatin structure via the addition of acetyl groups to histone proteins alters the nucleoprotein affinity, resulting in

A. Permanent destruction of the DNA template
B. Relaxation of chromatin structure to permit transcription
✓
C. Dense packing of DNA into transcriptionally silent heterochromatin
D. The immediate export of histones into the cytoplasm

📝 Explanation

Acetylation neutralizes the positive charges on histones, weakening their grip on DNA and allowing transcription machinery to bind.

📖 Additional Information

  • Permanent destruction of the DNA template
  • Relaxation of chromatin structure to permit transcription
  • Dense packing of DNA into transcriptionally silent heterochromatin
  • The immediate export of histones into the cytoplasm

Acetylation neutralizes the positive charges on histones, weakening their grip on DNA and allowing transcription machinery to bind.

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