BIO NMDCAT Chromosomes

nmdcat.online July 4, 2026

47. A primary reason for the highly negative net charge exhibited by the DNA molecule wrapped around histones is the structural presence of

A. Basic nitrogenous base groups

B. Ionized phosphate functional groups

✓

C. Deoxyribose carbon clusters

D. Disulfide covalent bridges

📝 Explanation

The sugar-phosphate backbone of DNA contains repeated phosphate groups that carry negative charges at physiological pH, allowing complementary electrostatic binding to basic histones.

📖 Additional Information

Basic nitrogenous base groups
Ionized phosphate functional groups
Deoxyribose carbon clusters
Disulfide covalent bridges

The sugar-phosphate backbone of DNA contains repeated phosphate groups that carry negative charges at physiological pH, allowing complementary electrostatic binding to basic histones.

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