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BIO NMDCAT Ribonucleic acid (RNA)
nmdcat.online July 3, 2026

52. The functional significance of the 2′ hydroxyl group on the ribose ring of RNA is that it

A. Permits RNA to act as a genetic repository in all living systems
B. Enables certain RNA molecules to display enzymatic activity
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C. Prevents RNA from forming loops and secondary configurations
D. Forces RNA to adopt a rigid B-form double helical geometry

📝 Explanation

The chemical reactivity of the 2'-OH group allows RNA to participate in catalytic mechanisms, giving rise to ribozymes.

📖 Additional Information

  • Permits RNA to act as a genetic repository in all living systems
  • Enables certain RNA molecules to display enzymatic activity
  • Prevents RNA from forming loops and secondary configurations
  • Forces RNA to adopt a rigid B-form double helical geometry

The chemical reactivity of the 2'-OH group allows RNA to participate in catalytic mechanisms, giving rise to ribozymes.

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