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BIO NMDCAT Conjugated molecules
nmdcat.online July 3, 2026

52. The primary consequence of an individual possessing mutated, non-functional LDL receptors on their cell surfaces is

A. Abnormally low levels of circulating blood lipids
B. Severe hypercholesterolemia and premature atherosclerosis
✓
C. Accelerated entry of cholesterol into peripheral cells
D. Total cessation of hepatic cholesterol production

📝 Explanation

Without working receptors, cells cannot internalize LDL particles via receptor-mediated endocytosis, causing cholesterol to build up in the blood.

📖 Additional Information

  • Abnormally low levels of circulating blood lipids
  • Severe hypercholesterolemia and premature atherosclerosis
  • Accelerated entry of cholesterol into peripheral cells
  • Total cessation of hepatic cholesterol production

Without working receptors, cells cannot internalize LDL particles via receptor-mediated endocytosis, causing cholesterol to build up in the blood.

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