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BIO NMDCAT Cytoplasmic Organelles
nmdcat.online July 4, 2026

54. In eukaryotic protein secretion, the localized fusion of secretory vesicles with the target membrane is coordinated by the structural interaction of

A. Importin and exportin heterodimers
B. Specific Rab GTPases and tethering proteins
✓
C. Cardiolipin microdomains on the bilayer
D. Nuclear lamins complexed with actin filaments

📝 Explanation

Rab GTPases serve as molecular tags on transport vesicles, interacting with specific tethering complexes on target membranes to ensure docking accuracy.

📖 Additional Information

  • Importin and exportin heterodimers
  • Specific Rab GTPases and tethering proteins
  • Cardiolipin microdomains on the bilayer
  • Nuclear lamins complexed with actin filaments

Rab GTPases serve as molecular tags on transport vesicles, interacting with specific tethering complexes on target membranes to ensure docking accuracy.

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