BIO NMDCAT Inhibitors

nmdcat.online July 13, 2026

6. During metabolism, heavy metal ions commonly reduce enzyme activity by

A. Binding to sulfhydryl groups and altering enzyme structure

✓

B. Increasing substrate concentration

C. Acting as enzyme cofactors

D. Converting enzymes into products

📝 Explanation

Heavy metals such as mercury and lead bind to sulfhydryl (-SH) groups, distorting enzyme structure and causing irreversible inhibition. The remaining options are incorrect mechanisms. Concept tested: Heavy metal inhibition.

📖 Additional Information

Binding to sulfhydryl groups and altering enzyme structure
Increasing substrate concentration
Acting as enzyme cofactors
Converting enzymes into products

Heavy metals such as mercury and lead bind to sulfhydryl (-SH) groups, distorting enzyme structure and causing irreversible inhibition. The remaining options are incorrect mechanisms. Concept tested: Heavy metal inhibition.

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