BIO NMDCAT Ribonucleic acid (RNA)

nmdcat.online July 3, 2026

72. The enzymatic synthesis of RNA using a DNA template is fundamentally distinct from DNA replication because transcription

A. Does not require a pre-existing 3'-OH primer

✓

B. Occurs in the 3' to 5' direction along the new strand

C. Proceeds without melting the double-stranded DNA molecule

D. Incorporates deoxyribonucleoside triphosphates

📝 Explanation

RNA polymerases possess the unique biochemical capacity to initiate the synthesis of a new polynucleotide chain completely de novo.

📖 Additional Information

Does not require a pre-existing 3'-OH primer
Occurs in the 3' to 5' direction along the new strand
Proceeds without melting the double-stranded DNA molecule
Incorporates deoxyribonucleoside triphosphates

RNA polymerases possess the unique biochemical capacity to initiate the synthesis of a new polynucleotide chain completely de novo.

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